产品货号:
Z37752
中文名称:
Hu CD38 Purified抗体
英文名称:
Anti-Hu CD38 Purified Antibody (Clone#HIT2)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Hu CD38 Purified Antibody (Clone#HIT2) |
指标别名 | ADP ribosyl cyclase 1;cADPr hydrolase 1;CD38;CD38 molecule;Cyclic ADP ribose hydrolase 1;T10 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | FCM,WB,IHC,IHC-F |
基因名称 | CD38 |
克隆号 | HIT2 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human thymocytes in foetus.The mouse monoclonal antibody HIT2 reacts with an extracellular epitope of CD38,a 45kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes;it is an antigenic marker of lymphoid cells.Its binding is blocked by daratumumab. |
计算分子量 | 34kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation,proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells.Another role of CD38 is provided by enzymatic activity of its extracellular part.CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose,as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase,thus affecting levels of calcium-mobilizing metabolites.ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration. |
Uniprot ID | P28907 |
基因名全称 | CD38 molecule |
蛋白名全称 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
推荐稀释比 | Immunohistochemistry (paraffin sections):10μg/mL. Western blotting:2μg/mL;positive control:RAJI human cell line,non-reducing conditions. Flow cytometry:1~4μg/mL |
相关搜索:Hu CD38 Purified抗体,Hu CD38 Purified单抗,Anti-Hu CD38 Purified Antibody (Clone#HIT2)